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Total chemical synthesis of human interferon alpha-2b via native chemical ligation
Interferon-alpha (IFNα) is a cytokine that orchestrates innate and adaptive immune responses, and potently inhibits proliferation of normal and tumor cells. These properties have warranted the use of IFNα in clinical practice for the treatment of several viral infections and malignancies. However, o...
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| Udgivet i: | J Pept Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480187/ https://ncbi.nlm.nih.gov/pubmed/25810135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.2760 |
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