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Total chemical synthesis of human interferon alpha-2b via native chemical ligation

Interferon-alpha (IFNα) is a cytokine that orchestrates innate and adaptive immune responses, and potently inhibits proliferation of normal and tumor cells. These properties have warranted the use of IFNα in clinical practice for the treatment of several viral infections and malignancies. However, o...

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Detalhes bibliográficos
Publicado no:J Pept Sci
Main Authors: Li, Jing, Lehmann, Clara, Chen, Xishan, Romerio, Fabio, Lu, Wuyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480187/
https://ncbi.nlm.nih.gov/pubmed/25810135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.2760
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