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Hydrogels Cross-Linked by Native Chemical Ligation

We describe the use of native chemical ligation (NCL) reaction to covalently cross-link soluble polymers into hydrogels. Macromonomers consisting of a four-armed poly(ethylene glycol) (PEG) core end-functionalized with either thioester or N-terminal cysteine peptide were designed and synthesized. Up...

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Detalhes bibliográficos
Main Authors: Hu, Bi-Huang, Su, Jing, Messersmith, Phillip B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790863/
https://ncbi.nlm.nih.gov/pubmed/19601644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm900366e
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