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Effectiveness, safety and costs of orphan drugs: an evidence-based review
INTRODUCTION: Several orphan drugs have been approved by the European Medicines Agency (EMA) over the past two decades. However, the drugs are expensive, and in some instances, the evidence for effectiveness is not convincing at the time of regulatory approval. Our objective was to evaluate the clin...
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| Publicado no: | BMJ Open |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480037/ https://ncbi.nlm.nih.gov/pubmed/26109112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-007199 |
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