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Effectiveness, safety and costs of orphan drugs: an evidence-based review

INTRODUCTION: Several orphan drugs have been approved by the European Medicines Agency (EMA) over the past two decades. However, the drugs are expensive, and in some instances, the evidence for effectiveness is not convincing at the time of regulatory approval. Our objective was to evaluate the clin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMJ Open
Egile Nagusiak: Onakpoya, Igho J, Spencer, Elizabeth A, Thompson, Matthew J, Heneghan, Carl J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMJ Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480037/
https://ncbi.nlm.nih.gov/pubmed/26109112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-007199
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