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Effectiveness, safety and costs of orphan drugs: an evidence-based review
INTRODUCTION: Several orphan drugs have been approved by the European Medicines Agency (EMA) over the past two decades. However, the drugs are expensive, and in some instances, the evidence for effectiveness is not convincing at the time of regulatory approval. Our objective was to evaluate the clin...
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| Publicat a: | BMJ Open |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMJ Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480037/ https://ncbi.nlm.nih.gov/pubmed/26109112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-007199 |
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