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Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation
Autophagy plays a central role in various disease processes. However, its contribution to inflammatory arthritides such as rheumatoid arthritis (RA) is unclear. We observed that autophagy is engaged in the K/BxN serum transfer model of RA but autophagic flux is severely impaired. Metformin is an ant...
Tallennettuna:
Julkaisussa: | J Rheum Dis Treat |
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Päätekijät: | , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2015
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479345/ https://ncbi.nlm.nih.gov/pubmed/26120598 |
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