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Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation

Autophagy plays a central role in various disease processes. However, its contribution to inflammatory arthritides such as rheumatoid arthritis (RA) is unclear. We observed that autophagy is engaged in the K/BxN serum transfer model of RA but autophagic flux is severely impaired. Metformin is an ant...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Rheum Dis Treat
Päätekijät: Yan, Huimin, Zhou, Hui-fang, Hu, Ying, Pham, Christine T.N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479345/
https://ncbi.nlm.nih.gov/pubmed/26120598
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