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Synergistic effect of antiangiogenic nanotherapy combined with methotrexate in the treatment of experimental inflammatory arthritis

AIM: This study examines the effect of combining the antiangiogenic effect of α(v)β(3)-targeted fumagillin nanoparticles with the conventional antirheumatic drug methotrexate for the treatment of inflammatory arthritis. METHOD: Arthritis was induced in mice by K/BxN serum transfer, and disease activ...

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Detalhes bibliográficos
Main Authors: Zhou, Hui-fang, Hu, Grace, Wickline, Samuel A, Lanza, Gregory M, Pham, Christine TN
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035945/
https://ncbi.nlm.nih.gov/pubmed/20874021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.78
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