AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy

We have recently shown that in diabetic OVE26 mice (type I diabetes), the AMP-activated protein kinase (AMPK) is reduced along with cardiac dysfunction and decreased cardiac autophagy. Genetic inhibition of AMPK in cardiomyocytes attenuates cardiac autophagy, exacerbates cardiac dysfunction and incr...

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Hlavní autoři: Xie, Zhonglin, He, Chaoyong, Zou, Ming-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
Autophagic Punctum
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210311/
https://ncbi.nlm.nih.gov/pubmed/21685727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16740
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