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AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
We have recently shown that in diabetic OVE26 mice (type I diabetes), the AMP-activated protein kinase (AMPK) is reduced along with cardiac dysfunction and decreased cardiac autophagy. Genetic inhibition of AMPK in cardiomyocytes attenuates cardiac autophagy, exacerbates cardiac dysfunction and incr...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210311/ https://ncbi.nlm.nih.gov/pubmed/21685727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16740 |
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