Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

OBJECTIVE: Autophagy is a critical cellular system for removal of aggregated proteins and damaged organelles. Although dysregulated autophagy is implicated in the development of heart failure, the role of autophagy in the development of diabetic cardiomyopathy has not been studied. We investigated w...

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Detalhes bibliográficos
Main Authors: Xie, Zhonglin, Lau, Kai, Eby, Bonnie, Lozano, Pedro, He, Chaoyong, Pennington, Becky, Li, Hongliang, Rathi, Shradha, Dong, Yunzhou, Tian, Rong, Kem, David, Zou, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114402/
https://ncbi.nlm.nih.gov/pubmed/21562078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0351
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