Suppression of AMP‐activated protein kinase reverses osteoprotegerin‐induced inhibition of osteoclast differentiation by reducing autophagy

OBJECTIVES: Osteoclasts (OC) are unique terminally differentiated cells whose primary function is bone resorption. We previously showed that osteoprotegerin (OPG) inhibits OC differentiation in vitro by enhancing autophagy via the adenosine monophosphate‐activated protein kinase (AMPK)/mTOR/p70S6K s...

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書目詳細資料
發表在:Cell Prolif
Main Authors: Tong, Xishuai, Zhang, Chuang, Wang, Dong, Song, Ruilong, Ma, Yonggang, Cao, Ying, Zhao, Hongyan, Bian, Jianchun, Gu, Jianhong, Liu, Zongping
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985670/
https://ncbi.nlm.nih.gov/pubmed/31696568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12714
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