Suppression of AMP‐activated protein kinase reverses osteoprotegerin‐induced inhibition of osteoclast differentiation by reducing autophagy

OBJECTIVES: Osteoclasts (OC) are unique terminally differentiated cells whose primary function is bone resorption. We previously showed that osteoprotegerin (OPG) inhibits OC differentiation in vitro by enhancing autophagy via the adenosine monophosphate‐activated protein kinase (AMPK)/mTOR/p70S6K s...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Tong, Xishuai, Zhang, Chuang, Wang, Dong, Song, Ruilong, Ma, Yonggang, Cao, Ying, Zhao, Hongyan, Bian, Jianchun, Gu, Jianhong, Liu, Zongping
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985670/
https://ncbi.nlm.nih.gov/pubmed/31696568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12714
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires