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Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells
BACKGROUND: Valosin containing protein (VCP) is a critical mediator of protein homeostasis and may represent a valuable therapeutic target for several forms of cancer. Overexpression of VCP occurs in many cancers, and often in a manner correlating with malignancy and poor outcome. Here, we analyzed...
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| Publicado no: | BMC Cancer |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479320/ https://ncbi.nlm.nih.gov/pubmed/26104798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1489-1 |
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