Anti-VEGFA Therapy Reduces Tumor Growth and Extends Survival in a Murine Model of Ovarian Granulosa Cell Tumor

Although angiogenesis has been proposed as a therapeutic target for the treatment of ovarian granulosa cell tumor (GCT), its potential has not been evaluated in controlled studies. To do so, we used the Pten(tm1Hwu/tm1Hwu); Ctnnb1(tm1Mmt/+);Amhr2(tm3(cre)Bhr/+) (PCA) mouse model, which develops GCTs...

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Bibliografske podrobnosti
Main Authors: Tsoi, Mayra, Laguë, Marie-Noëlle, Boyer, Alexandre, Paquet, Marilène, Nadeau, Marie-Ève, Boerboom, Derek
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660791/
https://ncbi.nlm.nih.gov/pubmed/23730402
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