Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis

Synergistic effects of dysregulation of the WNT/CTNNB1 and phosphatidylinositol 3-kinase (PI3K)/AKT pathways are thought to be important for the development and progression of many forms of cancer, including the granulosa cell tumor of the ovary. Sustained WNT/CTNNB1 signaling in Sertoli cells cause...

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Bibliographische Detailangaben
Hauptverfasser: Boyer, Alexandre, Paquet, Marilène, Laguë, Marie-Noëlle, Hermo, Louis, Boerboom, Derek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Carcinogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675650/
https://ncbi.nlm.nih.gov/pubmed/19237610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp051
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