Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression

The mechanisms of granulosa cell tumor (GCT) development may involve the dysregulation of signaling pathways downstream of follicle-stimulating hormone, including the phosphoinosite-3 kinase (PI3K)/AKT pathway. To test this hypothesis, a genetically engineered mouse model was created to derepress th...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Laguë, Marie-Noëlle, Paquet, Marilène, Fan, Heng-Yu, Kaartinen, M. Johanna, Chu, Simon, Jamin, Soazik P., Behringer, Richard R., Fuller, Peter J., Mitchell, Andrew, Doré, Monique, Huneault, Louis M., Richards, JoAnne S., Boerboom, Derek
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
Предметы:
Cancer Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577137/
https://ncbi.nlm.nih.gov/pubmed/18687666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn186
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы