Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection

We sought to determine the mechanisms by which influenza infection of human epithelial cells decreases cystic fibrosis transmembrane conductance regulator (CFTR) expression and function. We infected human bronchial epithelial (NHBE) cells and murine nasal epithelial (MNE) cells with various strains...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Londino, James David, Lazrak, Ahmed, Noah, James W., Aggarwal, Saurabh, Bali, Vedrana, Woodworth, Bradford A., Bebok, Zsuzsanna, Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478808/
https://ncbi.nlm.nih.gov/pubmed/25795456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268755
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