Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection

We sought to determine the mechanisms by which influenza infection of human epithelial cells decreases cystic fibrosis transmembrane conductance regulator (CFTR) expression and function. We infected human bronchial epithelial (NHBE) cells and murine nasal epithelial (MNE) cells with various strains...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Londino, James David, Lazrak, Ahmed, Noah, James W., Aggarwal, Saurabh, Bali, Vedrana, Woodworth, Bradford A., Bebok, Zsuzsanna, Matalon, Sadis
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2015
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478808/
https://ncbi.nlm.nih.gov/pubmed/25795456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268755
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