Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection

We sought to determine the mechanisms by which influenza infection of human epithelial cells decreases cystic fibrosis transmembrane conductance regulator (CFTR) expression and function. We infected human bronchial epithelial (NHBE) cells and murine nasal epithelial (MNE) cells with various strains...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Londino, James David, Lazrak, Ahmed, Noah, James W., Aggarwal, Saurabh, Bali, Vedrana, Woodworth, Bradford A., Bebok, Zsuzsanna, Matalon, Sadis
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2015
Sujets:
Research Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478808/
https://ncbi.nlm.nih.gov/pubmed/25795456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268755
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