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A quantitative multiplexed mass spectrometry assay for studying the kinetic of residue-specific histone acetylation
Histone acetylation is involved in gene regulation and, most importantly, aberrant regulation of histone acetylation is correlated with major human diseases. Although many lysine acetyltransferases (KATs) have been characterized as being capable of acetylating multiple lysine residues on histones, h...
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| Publicado en: | Methods |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477693/ https://ncbi.nlm.nih.gov/pubmed/25123533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.08.003 |
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