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Quantitating the Specificity and Selectivity of Gcn5-Mediated Acetylation of Histone H3

Lysine acetyltransferases (KATs) play a unique role in regulating gene transcription as well as maintaining the epigenetic state of the cell. KATs such as Gcn5 and p300/CBP can modify multiple residues on a single histone; however, order and specificity of acetylation can be altered by factors such...

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Bibliografiske detaljer
Main Authors: Kuo, Yin-Ming, Andrews, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578832/
https://ncbi.nlm.nih.gov/pubmed/23437046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054896
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