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A quantitative multiplexed mass spectrometry assay for studying the kinetic of residue-specific histone acetylation

Histone acetylation is involved in gene regulation and, most importantly, aberrant regulation of histone acetylation is correlated with major human diseases. Although many lysine acetyltransferases (KATs) have been characterized as being capable of acetylating multiple lysine residues on histones, h...

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Publicat a:Methods
Autors principals: Kuo, Yin-Ming, Henry, Ryan A., Andrews, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477693/
https://ncbi.nlm.nih.gov/pubmed/25123533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.08.003
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