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A quantitative multiplexed mass spectrometry assay for studying the kinetic of residue-specific histone acetylation

Histone acetylation is involved in gene regulation and, most importantly, aberrant regulation of histone acetylation is correlated with major human diseases. Although many lysine acetyltransferases (KATs) have been characterized as being capable of acetylating multiple lysine residues on histones, h...

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Dettagli Bibliografici
Pubblicato in:Methods
Autori principali: Kuo, Yin-Ming, Henry, Ryan A., Andrews, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477693/
https://ncbi.nlm.nih.gov/pubmed/25123533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.08.003
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