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Differences in Specificity and Selectivity Between CBP and p300 Acetylation of Histone H3 and H3/H4

[Image: see text] Although p300 and CBP lysine acetyltransferases are often treated interchangeably, the inability of one enzyme to compensate for the loss of the other suggests unique roles for each. As these deficiencies coincide with aberrant levels of histone acetylation, we hypothesized that th...

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Autori principali: Henry, Ryan A., Kuo, Yin-Ming, Andrews, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2013
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756530/
https://ncbi.nlm.nih.gov/pubmed/23862699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400684q
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