XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage

Xeroderma pigmentosum group D (XPD/ERCC2) encodes an ATP-dependent helicase that plays essential roles in both transcription and nucleotide excision repair of nuclear DNA, however, whether or not XPD exerts similar functions in mitochondria remains elusive. In this study, we provide the first eviden...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Liu, Jing, Fang, Hongbo, Chi, Zhenfen, Wu, Zan, Wei, Di, Mo, Dongliang, Niu, Kaifeng, Balajee, Adayabalam S., Hei, Tom K., Nie, Linghu, Zhao, Yongliang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477675/
https://ncbi.nlm.nih.gov/pubmed/25969448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv472
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