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XPD-dependent activation of apoptosis in response to triplex-induced DNA damage

DNA sequences capable of forming triplexes are prevalent in the human genome and have been found to be intrinsically mutagenic. Consequently, a balance between DNA repair and apoptosis is critical to counteract their effect on genomic integrity. Using triplex-forming oligonucleotides to syntheticall...

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Detalhes bibliográficos
Main Authors: Kaushik Tiwari, Meetu, Rogers, Faye A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799437/
https://ncbi.nlm.nih.gov/pubmed/23913414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt670
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