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RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity
Human RecQL4 helicase plays critical roles in the maintenance of genomic stability. Mutations in RecQL4 helicase results in three clinically related autosomal recessive disorders: Rothmund–Thomson syndrome (RTS), RAPADILINO, and Baller–Gerold syndrome. In addition to several premature aging features...
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| Опубликовано в: : | Oncogenesis |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6134139/ https://ncbi.nlm.nih.gov/pubmed/30206236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0080-4 |
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