Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo

Etheno DNA adducts are a prevalent type of DNA damage caused by vinyl chloride (VC) exposure and oxidative stress. Etheno adducts are mutagenic and may contribute to the initiation of several pathologies; thus, elucidating the pathways by which they induce cellular transformation is critical. Althou...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chang, Shiou-chi, Fedeles, Bogdan I., Wu, Jie, Delaney, James C., Li, Deyu, Zhao, Linlin, Christov, Plamen P., Yau, Emily, Singh, Vipender, Jost, Marco, Drennan, Catherine L., Marnett, Lawrence J., Rizzo, Carmelo J., Levine, Stuart S., Guengerich, F. Peter, Essigmann, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477646/
https://ncbi.nlm.nih.gov/pubmed/25837992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv243
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