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Basis of Miscoding of the DNA Adduct N(2),3-Ethenoguanine by Human Y-family DNA Polymerases
N(2),3-Ethenoguanine (N(2),3-ϵG) is one of the exocyclic DNA adducts produced by endogenous processes (e.g. lipid peroxidation) and exposure to bioactivated vinyl monomers such as vinyl chloride, which is a known human carcinogen. Existing studies exploring the miscoding potential of this lesion are...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471744/ https://ncbi.nlm.nih.gov/pubmed/22910910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403253 |
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