N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

[Image: see text] Treatment of filamentous fungal infections relies on a limited repertoire of antifungal agents. Compounds possessing novel modes of action are urgently required. N-myristoylation is a ubiquitous modification of eukaryotic proteins. The enzyme N-myristoyltransferase (NMT) has been c...

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Publicado no:ACS Chem Biol
Main Authors: Fang, Wenxia, Robinson, David A., Raimi, Olawale G., Blair, David E., Harrison, Justin R., Lockhart, Deborah E. A., Torrie, Leah S., Ruda, Gian Filippo, Wyatt, Paul G., Gilbert, Ian H., van Aalten, Daan M. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477619/
https://ncbi.nlm.nih.gov/pubmed/25706802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5008647
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