Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target

Aspergillus fumigatus is the causative agent of IA (invasive aspergillosis) in immunocompromised patients. It possesses a cell wall composed of chitin, glucan and galactomannan, polymeric carbohydrates synthesized by processive glycosyltransferases from intracellular sugar nucleotide donors. Here we...

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Hlavní autoři: Fang, Wenxia, Du, Ting, Raimi, Olawale G., Hurtado-Guerrero, Ramón, Mariño, Karina, Ibrahim, Adel F. M., Albarbarawi, Osama, Ferguson, Michael A. J., Jin, Cheng, Van Aalten, Daan M. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2013
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763426/
https://ncbi.nlm.nih.gov/pubmed/23844980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130053
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