N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

[Image: see text] Treatment of filamentous fungal infections relies on a limited repertoire of antifungal agents. Compounds possessing novel modes of action are urgently required. N-myristoylation is a ubiquitous modification of eukaryotic proteins. The enzyme N-myristoyltransferase (NMT) has been c...

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Bibliografiset tiedot
Julkaisussa:ACS Chem Biol
Päätekijät: Fang, Wenxia, Robinson, David A., Raimi, Olawale G., Blair, David E., Harrison, Justin R., Lockhart, Deborah E. A., Torrie, Leah S., Ruda, Gian Filippo, Wyatt, Paul G., Gilbert, Ian H., van Aalten, Daan M. F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2015
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477619/
https://ncbi.nlm.nih.gov/pubmed/25706802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5008647
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