Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia

Several lines of evidence implicate excess glucagon secretion in the elevated rates of hepatic glucose production (HGP), hyperglycemia, and ketosis characteristic of uncontrolled insulin-deficient diabetes (uDM), but whether hyperglucagonemia is required for hyperglycemia in this setting is unknown....

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Diabetes
Glavni autori: Meek, Thomas H., Dorfman, Mauricio D., Matsen, Miles E., Fischer, Jonathan D., Cubelo, Alexis, Kumar, Monica R., Taborsky, Gerald J., Morton, Gregory J.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2015
Teme:
Metabolism
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477352/
https://ncbi.nlm.nih.gov/pubmed/25633417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1562
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items