Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice.

Lignende værker

• Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.
  af: Prendergast, G C, et al.
  Udgivet: (1994)
• Identification of Ras farnesyltransferase inhibitors by microbial screening.
  af: Hara, M, et al.
  Udgivet: (1993)
• Plant farnesyltransferase can restore yeast Ras signaling and mating.
  af: Yalovsky, S, et al.
  Udgivet: (1997)
• Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity.
  af: Lebowitz, P F, et al.
  Udgivet: (1995)
• Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans.
  af: Hara, M, et al.
  Udgivet: (1995)