Voltage-gated Na(+) Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling

Functional expression of voltage-gated Na(+) channels (VGSCs) has been demonstrated in multiple cancer cell types where channel activity induces invasive activity. The signaling mechanisms by which VGSCs promote oncogenesis remain poorly understood. We explored the signal transduction process critic...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: House, Carrie D., Wang, Bi-Dar, Ceniccola, Kristin, Williams, Russell, Simaan, May, Olender, Jacqueline, Patel, Vyomesh, Baptista-Hon, Daniel T., Annunziata, Christina M., Silvio Gutkind, J., Hales, Tim G., Lee, Norman H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476109/
https://ncbi.nlm.nih.gov/pubmed/26096612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11541
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires