Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.

Two lines of transgenic (Tg) mice expressing high (H) levels of the mutant P101L prion protein (PrP) developed a neurologic illness and central nervous system pathology indistinguishable from experimental murine scrapie; these mice were designated Tg(MoPrP-P101L)H. Brain homogenates from Tg(MoPrP-P1...

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Detalhes bibliográficos
Main Authors: Hsiao, K K, Groth, D, Scott, M, Yang, S L, Serban, H, Rapp, D, Foster, D, Torchia, M, Dearmond, S J, Prusiner, S B
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44760/
https://ncbi.nlm.nih.gov/pubmed/7916462
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