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Drosophila DBT Autophosphorylation of Its C-Terminal Domain Antagonized by SPAG and Involved in UV-Induced Apoptosis

Drosophila DBT and vertebrate CKIε/δ phosphorylate the period protein (PER) to produce circadian rhythms. While the C termini of these orthologs are not conserved in amino acid sequence, they inhibit activity and become autophosphorylated in the fly and vertebrate kinases. Here, sites of C-terminal...

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Pubblicato in:Mol Cell Biol
Autori principali: Fan, Jin-Yuan, Means, John C., Bjes, Edward S., Price, Jeffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475922/
https://ncbi.nlm.nih.gov/pubmed/25939385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00390-15
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