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Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy

While circadian dysfunction and neurodegeneration are correlated, the mechanism for this is not understood. It is not known if age-dependent circadian dysfunction leads to neurodegeneration or vice-versa, and the proteins that mediate the effect remain unidentified. Here, we show that the knock-down...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Means, John C., Venkatesan, Anandakrishnan, Gerdes, Bryan, Fan, Jin-Yuan, Bjes, Edward S., Price, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423883/
https://ncbi.nlm.nih.gov/pubmed/25951229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005171
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