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A Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function

Doubletime (DBT) has an essential circadian role in Drosophila melanogaster because it phosphorylates Period (PER). In order to determine if DBT antagonism can produce distinct effects in the cytosol and nucleus, forms of a dominant negative DBT(K/R) with these two alternative localizations were pro...

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Detalhes bibliográficos
Publicado no:J Biol Rhythms
Main Authors: Venkatesan, Anandakrishnan, Fan, Jin-Yuan, Nauman, Christopher, Price, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730409/
https://ncbi.nlm.nih.gov/pubmed/26082158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730415588189
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