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A Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function

Doubletime (DBT) has an essential circadian role in Drosophila melanogaster because it phosphorylates Period (PER). In order to determine if DBT antagonism can produce distinct effects in the cytosol and nucleus, forms of a dominant negative DBT(K/R) with these two alternative localizations were pro...

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Détails bibliographiques
Publié dans:J Biol Rhythms
Auteurs principaux: Venkatesan, Anandakrishnan, Fan, Jin-Yuan, Nauman, Christopher, Price, Jeffrey L.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730409/
https://ncbi.nlm.nih.gov/pubmed/26082158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730415588189
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