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Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9
The serine/threonine kinase mTORC1 regulates cellular homeostasis in response to many cues, such as nutrient status and energy level. Amino acids induce mTORC1 activation on lysosomes via the small Rag GTPases and the Ragulator complex, thereby controlling protein translation and cell growth. Here,...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475919/ https://ncbi.nlm.nih.gov/pubmed/25963655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00125-15 |
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