PARK3 Influences Age at Onset in Parkinson Disease: A Genome Scan in the GenePD Study

Parkinson disease (PD) is a late-onset neurodegenerative disorder. The mean age at onset is 61 years, but the disease can range from juvenile cases to cases in the 8th or 9th decade of life. The parkin gene on chromosome 6q and loci on chromosome 1p35-36 and 1p36 are responsible for some cases of au...

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Auteurs principaux: DeStefano, Anita L., Lew, Mark F., Golbe, Lawrence I., Mark, Margery H., Lazzarini, Alice M., Guttman, Mark, Montgomery, Erwin, Waters, Cheryl H., Singer, Carlos, Watts, Ray L., Currie, Lillian J., Wooten, G. Frederick, Maher, Nancy E., Wilk, Jemma B., Sullivan, Kristin M., Slater, Karen M., Saint-Hilaire, Marie H., Feldman, Robert G., Suchowersky, Oksana, Lafontaine, Anne-Louise, Labelle, Nancy, Growdon, John H., Vieregge, Peter, Pramstaller, Peter P., Klein, Christine, Hubble, Jean P., Reider, Carson R., Stacy, Mark, MacDonald, Marcy E., Gusella, James F., Myers, Richard H.
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2002
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC447587/
https://ncbi.nlm.nih.gov/pubmed/11920285
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