Donor Requirements for Regulatory T Cell Suppression of Murine Graft Versus Host Disease

Adoptive transfer of freshly isolated natural occurring CD4+CD25+FoxP3+ regulatory T cells (Treg) prevents graft versus host disease (GvHD) in several animal models and following hematopoietic cell transplantation (HCT) in clinical trials. Donor derived Treg have been mainly used as they share the s...

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Publicado en:J Immunol
Autores principales: Pierini, Antonio, Colonna, Lucrezia, Alvarez, Maite, Schneidawind, Dominik, Nishikii, Hidekazu, Baker, Jeanette, Pan, Yuqiong, Florek, Mareike, Kim, Byung-Su, Negrin, Robert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475671/
https://ncbi.nlm.nih.gov/pubmed/25994967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402861
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