Donor Requirements for Regulatory T Cell Suppression of Murine Graft Versus Host Disease

Adoptive transfer of freshly isolated natural occurring CD4+CD25+FoxP3+ regulatory T cells (Treg) prevents graft versus host disease (GvHD) in several animal models and following hematopoietic cell transplantation (HCT) in clinical trials. Donor derived Treg have been mainly used as they share the s...

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Bibliographic Details
Published in:J Immunol
Main Authors: Pierini, Antonio, Colonna, Lucrezia, Alvarez, Maite, Schneidawind, Dominik, Nishikii, Hidekazu, Baker, Jeanette, Pan, Yuqiong, Florek, Mareike, Kim, Byung-Su, Negrin, Robert S.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475671/
https://ncbi.nlm.nih.gov/pubmed/25994967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402861
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