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Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs

Despite the significant progress made in recent years, the computation of the complete set of elementary flux modes of large or even genome-scale metabolic networks is still impossible. We introduce a novel approach to speed up the calculation of elementary flux modes by including transcriptional re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jungreuthmayer, Christian, Ruckerbauer, David E., Gerstl, Matthias P., Hanscho, Michael, Zanghellini, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475075/
https://ncbi.nlm.nih.gov/pubmed/26091045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129840
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