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Metabolomics integrated elementary flux mode analysis in large metabolic networks

Elementary flux modes (EFMs) are non-decomposable steady-state pathways in metabolic networks. They characterize phenotypes, quantify robustness or identify engineering targets. An EFM analysis (EFMA) is currently restricted to medium-scale models, as the number of EFMs explodes with the network...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gerstl, Matthias P., Ruckerbauer, David E., Mattanovich, Diethard, Jungreuthmayer, Christian, Zanghellini, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354105/
https://ncbi.nlm.nih.gov/pubmed/25754258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08930
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