Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs

Despite the significant progress made in recent years, the computation of the complete set of elementary flux modes of large or even genome-scale metabolic networks is still impossible. We introduce a novel approach to speed up the calculation of elementary flux modes by including transcriptional re...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Jungreuthmayer, Christian, Ruckerbauer, David E., Gerstl, Matthias P., Hanscho, Michael, Zanghellini, Jürgen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475075/
https://ncbi.nlm.nih.gov/pubmed/26091045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129840
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