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Designing optimal cell factories: integer programming couples elementary mode analysis with regulation
BACKGROUND: Elementary mode (EM) analysis is ideally suited for metabolic engineering as it allows for an unbiased decomposition of metabolic networks in biologically meaningful pathways. Recently, constrained minimal cut sets (cMCS) have been introduced to derive optimal design strategies for strai...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560272/ https://ncbi.nlm.nih.gov/pubmed/22898474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-103 |
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