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Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence

Much like replicative senescence, the irreversible cell-cycle arrest induced by eroded telomeres, accelerated senescence occurs when replicative cells suffer irreparable DNA double-strand breaks (DSBs). Along with apoptosis and necrosis, senescence is a desirable outcome in cancer treatment with ion...

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Podrobná bibliografie
Vydáno v:Int J High Throughput Screen
Hlavní autoři: Labay, Edwardine, Efimova, Elena V, Quarshie, Benjamin K, Golden, Daniel W, Weichselbaum, Ralph R, Kron, Stephen J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474479/
https://ncbi.nlm.nih.gov/pubmed/26097382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJHTS.S17076
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