Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors

Persistent DNA double strand breaks (DSBs) may determine the anti-tumor effects of ionizing radiation (IR) by inducing apoptosis, necrosis, mitotic catastrophe or permanent growth arrest. Ionizing radiation (IR) induces rapid modification of megabase chromatin domains surrounding double strand break...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Efimova, Elena V., Mauceri, Helena J., Golden, Daniel W., Labay, Edwardine, Bindokas, Vytautas P., Darga, Thomas E., Chakraborty, Chaitali, Andrade, Juan Camilo Barreto, Crawley, Clayton, Sutton, Harold G., Kron, Stephen J., Weichselbaum, Ralph R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912962/
https://ncbi.nlm.nih.gov/pubmed/20610628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4224
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