Linking Cancer Metabolism to DNA Repair and Accelerated Senescence

Conventional wisdom ascribes metabolic reprogramming in cancer to meeting increased demands for intermediates to support rapid proliferation. Prior models have proposed benefits toward cell survival, immortality and stress resistance while the recent discovery of oncometabolites has shifted attentio...

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Udgivet i:Mol Cancer Res
Main Authors: Efimova, Elena V., Takahashi, Satoe, Shamsi, Noumaan A., Wu, Ding, Labay, Edwardine, Ulanovskaya, Olesya A., Weichselbaum, Ralph R., Kozmin, Sergey A., Kron, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755886/
https://ncbi.nlm.nih.gov/pubmed/26538285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0263
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