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Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence
Much like replicative senescence, the irreversible cell-cycle arrest induced by eroded telomeres, accelerated senescence occurs when replicative cells suffer irreparable DNA double-strand breaks (DSBs). Along with apoptosis and necrosis, senescence is a desirable outcome in cancer treatment with ion...
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| Pubblicato in: | Int J High Throughput Screen |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474479/ https://ncbi.nlm.nih.gov/pubmed/26097382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJHTS.S17076 |
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