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Genetic Determinants of Japanese Encephalitis Virus Vaccine Strain SA14-14-2 That Govern Attenuation of Virulence in Mice

The safety and efficacy of the live-attenuated Japanese encephalitis virus (JEV) SA14-14-2 vaccine are attributed to mutations that accumulated in the viral genome during its derivation. However, little is known about the contribution that is made by most of these mutations to virulence attenuation...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Gromowski, Gregory D., Firestone, Cai-Yen, Whitehead, Stephen S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474313/
https://ncbi.nlm.nih.gov/pubmed/25855730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00219-15
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